2-Chloro-6-methoxyisonicotinoyl chloride
2-Chloro-6-methoxyisonicotinoyl chloride
CAS: 116853-97-5
Molecular Formula: C7H5Cl2NO2
2-Chloro-6-methoxyisonicotinoyl chloride - Names and Identifiers
2-Chloro-6-methoxyisonicotinoyl chloride - Physico-chemical Properties
| Molecular Formula | C7H5Cl2NO2 |
| Molar Mass | 206.03 |
| Melting Point | 60°C |
| Boling Point | 60°C 0,07mm |
| Flash Point | 79°C/0.2mm |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.5560 |
2-Chloro-6-methoxyisonicotinoyl chloride - Risk and Safety
| Risk Codes | R34 - Causes burns R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 3265 |
| Hazard Note | Corrosive |
| Hazard Class | 8 |
| Packing Group | II |
2-Chloro-6-methoxyisonicotinoyl chloride - Reference Information
| Application | 2-chloro-6-methoxyisonicotinoyl chloride can be used as an intermediate in pharmaceutical synthesis. It is prepared by the reaction of 2-chloro-6-methoxypyridine-4-carboxylic acid and thionyl chloride, it can be used to prepare the compound 2-chloro-6-methoxypyridine-4-carboxylic acid tert-butyl ester. |
| preparation | 2-chloro -6-methoxyisonicinoyl chloride is prepared as follows: 2-chloro -6-methoxypyridine -4-carboxylic acid (3.96g) is added to thionyl chloride (40ml), and heated and refluxed for 2 hours. Vacuum evaporates excess thionyl chloride, and evaporates the residue twice with dichloromethane to obtain 2-chloro-6-methoxyisonicotinoyl chloride, which is an almost colorless oil (4.17g). |
Last Update：2024-04-10 22:29:15
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View History
2-Chloro-6-methoxyisonicotinoyl chloride
338967-16-1
4-[(4-氯-2-嘧啶基)氨基]苯腈
3-(4-HYDRAZINYLPHENYL)PROPANOIC ACID HYDROCHLORIDE
(S)-2-(2,5-dichlorophenyl)pyrrolidine hydrochloride
1H-吡咯并[3,2-b]吡啶-5-羧酸甲酯
2-氯-6-甲基-4-氧代-4H-吡啶并[1,2-A]嘧啶-3-甲醛
3-Benzofurancarboxylic acid, 2-[(2-hydroxyphenyl)methyl]-, methyl ester
1-CHLORO-4-[2-((4-METHOXYPHENYL)([(4-METHYLBENZOYL)OXY]IMINO)METHYL)CYCLOPROPYL]BENZENE
1-叔丁氧羰基-2,5-二氢-1H-吡咯-3-硼酸频哪醇酯
338967-16-1
4-[(4-氯-2-嘧啶基)氨基]苯腈
3-(4-HYDRAZINYLPHENYL)PROPANOIC ACID HYDROCHLORIDE
(S)-2-(2,5-dichlorophenyl)pyrrolidine hydrochloride
1H-吡咯并[3,2-b]吡啶-5-羧酸甲酯
2-氯-6-甲基-4-氧代-4H-吡啶并[1,2-A]嘧啶-3-甲醛
3-Benzofurancarboxylic acid, 2-[(2-hydroxyphenyl)methyl]-, methyl ester
1-CHLORO-4-[2-((4-METHOXYPHENYL)([(4-METHYLBENZOYL)OXY]IMINO)METHYL)CYCLOPROPYL]BENZENE
1-叔丁氧羰基-2,5-二氢-1H-吡咯-3-硼酸频哪醇酯